Bioorganic Chemistry

Synthesis, characterization, <em>in vitro</em> antimycobacterial and cytotoxicity evaluation, DFT calculations, molecular docking and ADME studies of new isomeric benzimidazole-1,2,3-triazole-quinoline hybrid mixtures

Publication date: December 2023Source: Bioorganic Chemistry, Volume 141Author(s): Nombulelo T.P. Nyoni, Nomagugu B. Ncube, Mbali X. Kubheka, Nompumelelo P. Mkhwanazi, Sibusiso Senzani, Thishana Singh, Matshawandile Tukulula

By ScienceDirect Publication: Bioorganic Chemistry, ago

Synthesis and biological evaluation of novel 3-(5-substituted-<em>1H</em>-indol-3-yl)pyrrolidine-2,5-dione derivatives with a dual affinity for serotonin 5-HT<sub>1A</sub> receptor and SERT

Publication date: December 2023Source: Bioorganic Chemistry, Volume 141Author(s): Martyna Z. Wróbel, Andrzej Chodkowski, Maciej Dawidowski, Agata Siwek, Katarzyna Stachowicz, Bernadeta Szewczyk, Gabriel Nowak, Grzegorz Satała, Andrzej J. Bojarski, Jadw…

By ScienceDirect Publication: Bioorganic Chemistry, ago

Synthesis of 3-sulfenylindole derivatives from 4-hydroxy-2<em>H</em>-chromene-2-thione and indole using oxidative cross-dehydrogenative coupling reaction and anti-proliferative activity study of some of their sulfone derivatives

Publication date: December 2023Source: Bioorganic Chemistry, Volume 141Author(s): Anjela Xalxo, Ujjwal Jyoti Goswami, Shilpi Sarkar, Thirukumaran Kandasamy, Kriti Mehta, Siddhartha S. Ghosh, Prasad V. Bharatam, Abu T. Khan

By ScienceDirect Publication: Bioorganic Chemistry, ago

New 2,4-dihydro-1H-1,2,4-triazole-3-selones and 3,3′-di(4H-1,2,4-triazolyl)diselenides. Synthesis, biological evaluation, and in silico studies as antibacterial and fungicidal agents

Publication date: December 2023Source: Bioorganic Chemistry, Volume 141Author(s): Rizvan K. oglu Askerov, Youness eL Bakri, Vladimir K. Osmanov, Evgeny V. Chipinsky, Sajjad Ahmad, Zanna V. Matsulevich, Galina N. Borisova, Olga V. Kuzina, Victor N. Khru…

By ScienceDirect Publication: Bioorganic Chemistry, ago

Synthesis by diastereomeric resolution, biochemical evaluation and molecular modelling of chiral 3-hydroxyl b-lactam microtubule-targeting agents for the treatment of triple negative breast and chemoresistant colorectal cancers

Publication date: December 2023Source: Bioorganic Chemistry, Volume 141Author(s): Eavan C. McLoughlin, Brendan Twamley, John E. O’Brien, Patricia Hannon Barroeta, Daniela M. Zisterer, Mary J. Meegan, Niamh M. O’Boyle

By ScienceDirect Publication: Bioorganic Chemistry, ago