Aging, Genetics, Gene Therapy & Genetic Disease, Cell Biology
Activation of mitochondrial unfolded protein response protects against multiple exogenous stressors
The mitochondrial unfolded protein response (mitoUPR) is an evolutionarily conserved pathway that responds to mitochondria insults through transcriptional changes, mediated by the transcription factor ATFS-1/ATF-5, which acts to restore mitochondrial …