Department of Animal Biology

Nature Immunology

Nature Immunology

B cells require exosomes

Nature Immunology, Published online: 28 June 2022; doi:10.1038/s41590-022-01260-9B cells require exosomes

By Laurie A. Dempsey, 3 years ago
Nature Immunology

Itaconate isomers add complexity

Nature Immunology, Published online: 28 June 2022; doi:10.1038/s41590-022-01258-3Itaconate isomers add complexity

By Nicholas J. Bernard, 3 years ago
Nature Immunology

Inflammatory macrophages

Nature Immunology, Published online: 28 June 2022; doi:10.1038/s41590-022-01261-8Inflammatory macrophages

By Ioana Visan, 3 years ago
Nature Immunology

LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition

Nature Immunology, Published online: 27 June 2022; doi:10.1038/s41590-022-01238-7LAG3 inhibits T cell activation, but exactly how it does so has been unclear given a lack of structural information. Here the authors provide the crystal …

By Qianqian Ming, 3 years ago
Nature Immunology

Extrathymic expression of Aire controls the induction of effective T<sub>H</sub>17 cell-mediated immune response to <i>Candida albicans</i>

Nature Immunology, Published online: 27 June 2022; doi:10.1038/s41590-022-01247-6Abramson and colleagues show that Aire+MHCII+ ILC3s sense, internalize and present Candida albicans and modulate the induction of C. albicans-specific TH1…

By Jan Dobeš, 3 years ago
Nature Immunology

Overcoming the LAG3 phase problem

Nature Immunology, Published online: 27 June 2022; doi:10.1038/s41590-022-01239-6Lymphocyte activation gene 3 (LAG3) is an important checkpoint inhibitor molecule of immunotherapeutic interest. New crystal structures of LAG3 provide im…

By Jan Petersen, 3 years ago
Nature Immunology

Extrathymic Aire primes <i>Candida</i>-specific T<sub>H</sub>17 cells

Nature Immunology, Published online: 27 June 2022; doi:10.1038/s41590-022-01252-9Extrathymic MHCII+Rorc+ Aire-expressing cells that share characteristics with type 3 innate lymphoid cells (ILC3s) internalize C. albicans and present its…

By Vasileios Oikonomou, 3 years ago
Nature Immunology

Neuroinflammation creates an immune regulatory niche at the meningeal lymphatic vasculature near the cribriform plate

Nature Immunology, Published online: 28 March 2022; doi:10.1038/s41590-022-01158-6Fabry and colleagues show that cribriform plate-resident lymphatic endothelial cells respond to neuroinflammatory signals by inducing functional changes …

By Martin Hsu, 4 years ago
Nature Immunology

B cells regulate hematopoietic stem cells via cholinergic signaling

Nature Immunology, Published online: 28 March 2022; doi:10.1038/s41590-022-01172-8B-cell-derived acetylcholine initiates a circuit that prompts bone marrow stromal cells to secrete factors that restrain the blood-forming activity of he…

By Sweta B. Patel, 4 years ago
Nature Immunology

Retention of immune cells in cribriform lymphatics is induced by neuroinflammation

Nature Immunology, Published online: 28 March 2022; doi:10.1038/s41590-022-01162-wCribriform plate-resident lymphatic endothelial cells respond to neuroinflammatory signals by inducing functional changes that enhance the capture and pr…

By Nature Immunology - Issue - nature.com science feeds, 4 years ago

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