Nature Immunology, Published online: 23 August 2022; doi:10.1038/s41590-022-01298-9Tissue-destructive fibroblasts in arthritis are driven by the transcription factor ETS1. Analysis of a cross-tissue, single-cell fibroblast dataset and …
Nature Immunology, Published online: 23 August 2022; doi:10.1038/s41590-022-01296-xThe inhibitory checkpoint molecule CTLA-4 is essential for regulatory T cell function. A new study highlights the differential manner in which CTLA-4 bi…
Nature Immunology, Published online: 23 August 2022; doi:10.1038/s41590-022-01303-1Shifting pathways
Nature Immunology, Published online: 23 August 2022; doi:10.1038/s41590-022-01305-zLeaky mitochondria
Nature Immunology, Published online: 23 August 2022; doi:10.1038/s41590-022-01307-xδγ T cells in tumorigenesis
Nature Immunology, Published online: 23 August 2022; doi:10.1038/s41590-022-01304-0Isotype matters
Nature Immunology, Published online: 23 August 2022; doi:10.1038/s41590-022-01306-yKetogenesis and COVID-19
Nature Immunology, Published online: 22 August 2022; doi:10.1038/s41590-022-01287-yThe STAT3 pathway is activated in B cells by interleukin-6 and interleukin-21; however, methylation of Lys140 prevents its dephosphorylation and deactiv…
Nature Immunology, Published online: 28 July 2022; doi:10.1038/s41590-022-01274-3Patients with cancer undergoing anti-PD-1 immune checkpoint blockade can experience immune-related adverse effects. Wherry and colleagues examined the imm…
Nature Immunology, Published online: 28 July 2022; doi:10.1038/s41590-022-01271-6Patients with partial recombination-activating gene (RAG) deficiency (pRD) present variable late-onset autoimmune clinical phenotypes. Walter and colleagu…