Nature Immunology, Published online: 31 August 2022; doi:10.1038/s41590-022-01288-xRoncagalli and colleagues use time-resolved high-throughput proteomic analyses to provide a comprehensive picture of the impact of ligand affinity on ea…
Nature Immunology, Published online: 31 August 2022; doi:10.1038/s41590-022-01297-wA key biochemical event that enables T cells to discriminate between TCR antigens of varying affinities and to respond only to high-affinity antigens is…
Nature Immunology, Published online: 29 August 2022; doi:10.1038/s41590-022-01292-1Maini and colleagues used bronchoalveolar lavage (BAL) samples from the lower respiratory tract of healthy donors obtained before the COVID-19 pandemic …
Nature Immunology, Published online: 25 August 2022; doi:10.1038/s41590-022-01294-zETS1 regulates tissue-remodeling properties of specific fibroblast subtypes in the synovium, gut and cancer and thus emerges as a novel cross-tissue the…
Nature Immunology, Published online: 25 August 2022; doi:10.1038/s41590-022-01300-4Hugh O. McDevitt 1930–2022
Nature Immunology, Published online: 24 August 2022; doi:10.1038/s41590-022-01291-2The role of eosinophils in response to cancer is not well understood. Here the authors document evidence that eosinophils contribute to the immune respo…
Nature Immunology, Published online: 24 August 2022; doi:10.1038/s41590-022-01290-3Type I interferons have been described to have protumor or antitumor functions depending on context. Here the authors show a protumor function for type …
Nature Immunology, Published online: 24 August 2022; doi:10.1038/s41590-022-01293-0The net effect of type I interferon (IFN-I) signaling on tumor control depends on various factors, including the potential engagement of adaptive antica…
Nature Immunology, Published online: 24 August 2022; doi:10.1038/s41590-022-01299-8Intestinal group 3 innate lymphoid (ILC3) cells exhibit increased mobility in response to flagellin-mediated inflammation. This ‘patrolling’ behavior pr…
Nature Immunology, Published online: 23 August 2022; doi:10.1038/s41590-022-01283-2Translational patient-oriented research is essential for understanding the immunopathology of SARS-CoV-2 and the varied host responses to this virus. Su…