Nature Immunology, Published online: 23 September 2022; doi:10.1038/s41590-022-01302-2During T cell activation, tRNA-m1A ‘writers’ TRMT61A and TRMT6 are upregulated to modify a group of early tRNA species and promote efficient translat…
Nature Immunology, Published online: 23 September 2022; doi:10.1038/s41590-022-01316-wImmunotherapeutic targeting of the surface glycoprotein CD19 has markedly improved outcomes in patients with relapsed and refractory B cell progenito…
Nature Immunology, Published online: 22 September 2022; doi:10.1038/s41590-022-01313-zPace and colleagues assessed the antibody titers, B cell and T cell memory response against SARS-COV-2 in mRNA-vaccinated individuals to show that re…
Nature Immunology, Published online: 22 September 2022; doi:10.1038/s41590-022-01301-3Naive T cells are quiescent but undergo dynamic changes upon antigenic activation. Li and colleagues show that upregulation of tRNA methyltransferase…
Nature Immunology, Published online: 22 September 2022; doi:10.1038/s41590-022-01312-0Zhang and colleagues use single-cell RNA sequencing on the nasal mucosa to identify cell subsets and molecules that specifically contribute to the pa…
Nature Immunology, Published online: 22 September 2022; doi:10.1038/s41590-022-01314-yAifantis and colleagues use leukemic cell lines to identify modulators of CD19 expression that have the potential to improve therapeutic strategies.
Nature Immunology, Published online: 22 September 2022; doi:10.1038/s41590-022-01309-9The explosion of single-cell and systems approaches in immunology risks leaving the uninitiated behind. This guide to systems immunology is designed …
Nature Immunology, Published online: 22 September 2022; doi:10.1038/s41590-022-01311-1Recent studies suggest that neutrophils can exhibit substantial function diversity. Here, Ostuni and colleagues perform immunophenotyping and transcr…
Nature Immunology, Published online: 06 September 2022; doi:10.1038/s41590-022-01308-wThrough access to healthy donors’ bronchoalveolar lavage (BAL) samples cryopreserved before the COVID-19 pandemic, we discovered CD4+ and CD8+ T cell…
Nature Immunology, Published online: 01 September 2022; doi:10.1038/s41590-022-01295-yHenao-Mejia and colleagues provide a detailed characterization of the 3D genome architecture of ILCs and demonstrate that ILC2 development and progre…