Nature Immunology, Published online: 22 December 2022; doi:10.1038/s41590-022-01375-zDe Jong and colleagues identify staphylococcal phosphatidylglycerol lipids as antigens for human CD1a-restricted T cells, which promote type 2 immune …
Nature Immunology, Published online: 21 December 2022; doi:10.1038/s41590-022-01374-0The factors controlling monocyte fate commitment toward macrophages versus dendritic cells are unclear. Here the authors show that ETV3 and ETV6 enabl…
Nature Immunology, Published online: 21 December 2022; doi:10.1038/s41590-022-01384-yCancer immunotherapies can be limited by terminally dysfunctional T cells in the tumor microenvironment. Here the authors present a model of stable hu…
Nature Immunology, Published online: 21 December 2022; doi:10.1038/s41590-022-01379-9Exhausted CD8+ T cells with diminished effector functions accumulate in tumors. Here, the authors show that hypoxia induces a suppressive phenotype in…
Nature Immunology, Published online: 19 December 2022; doi:10.1038/s41590-022-01367-zManthiram and colleagues analyze the peripheral blood, tonsils and adenoids in children undergoing tonsillectomy or adenoidectomy and find evidence of…
Nature Immunology, Published online: 19 December 2022; doi:10.1038/s41590-022-01371-3Betts and colleagues have developed a method for characterizing the HIV reservoir at the single-cell level to gain insight into the heterogeneous natu…
Nature Immunology, Published online: 15 December 2022; doi:10.1038/s41590-022-01370-4Modeling a rare bone marrow failure disorder due to haploinsufficiency for the MECOM transcription factor identifies a human hematopoietic stem cell r…
Nature Immunology, Published online: 12 December 2022; doi:10.1038/s41590-022-01369-xGoronzy and colleagues examine differences in naive CD4+ T cells from young and older adults to TCR stimulation. They find reduced HELIOS expression i…
Nature Immunology, Published online: 09 December 2022; doi:10.1038/s41590-022-01368-yZhang et al. describe how meningeal MAIT cells maintain meningeal barrier integrity via the secretion of antioxidants, which also limit neuroinflammat…
Nature Immunology, Published online: 09 December 2022; doi:10.1038/s41590-022-01397-7Author Correction: Heterogeneous plasma cells and long-lived subsets in response to immunization, autoantigen and microbiota