Nature Immunology, Published online: 19 January 2023; doi:10.1038/s41590-022-01412-xTH17 cells combat infection but can also drive pathological inflammation. A TH17 cell NLRP3–caspase-8–caspase-3–GSDME axis is now shown to release the …
Nature Immunology, Published online: 19 January 2023; doi:10.1038/s41590-022-01395-9Farber and colleagues examine the phenotypic, transcriptomic, clonal, and functional differences between tissue-resident T cells in various barrier tis…
Nature Immunology, Published online: 19 January 2023; doi:10.1038/s41590-022-01413-wReboldi and colleagues show that high-cholesterol diets influence IgA secretion. Cholesterol-derived metabolites act on plasma cell GPR183 receptors to…
Nature Immunology, Published online: 19 January 2023; doi:10.1038/s41590-022-01403-yColonna and colleagues report dysregulated gene expression in microglia harboring homozygous mutations of DAP12 from individuals with Nasu–Hakola disea…
Nature Immunology, Published online: 18 January 2023; doi:10.1038/s41590-023-01426-zAuthor Correction: Transmission of trained immunity and heterologous resistance to infections across generations
Nature Immunology, Published online: 17 January 2023; doi:10.1038/s41590-022-01409-6Exhausted effector T cells accumulate in tumors and are the intended targets of cancer immunotherapy. New data suggest that upon infiltration and subse…
Nature Immunology, Published online: 11 January 2023; doi:10.1038/s41590-022-01411-yA specialized subset of iNKT cells populates the skin in early life, where their supply of transferrin regulates iron metabolism to promote hair follic…
Nature Immunology, Published online: 11 January 2023; doi:10.1038/s41590-022-01401-0Starting on 19 September 2022, the very first ImmunOctoberfest conference took place in Raitenhaslach, Germany, bringing together scientists from all o…
Nature Immunology, Published online: 09 January 2023; doi:10.1038/s41590-022-01399-5Here, the authors show that a subset of NKT2 cells are programmed during thymic development at early postnatal ages to migrate to the skin, where they …
Nature Immunology, Published online: 09 January 2023; doi:10.1038/s41590-022-01394-wThe formation of an immunological synapse is central to the ability of NK cells to lyse target cells. Here the authors show that Nogo receptor 1 (NgR1)…