Nature Immunology, Published online: 17 August 2023; doi:10.1038/s41590-023-01599-7The DNA-binding domains of transcription factors have been well characterized, but whether their intrinsically disordered regions control cell fate is u…
Nature Immunology, Published online: 17 August 2023; doi:10.1038/s41590-023-01609-8In a genome-wide protein quantitative trait locus study, we identify the genetic determinants of the levels of 91 inflammation-related proteins in blood…
Nature Immunology, Published online: 17 August 2023; doi:10.1038/s41590-023-01590-2Thomas and colleagues examine preinfection baseline parameters of cellular and serologic immunity. Their findings collectively show that peripheral cell…
Nature Immunology, Published online: 14 August 2023; doi:10.1038/s41590-023-01575-1Garner et al. analyzed the single-cell transcriptome and TCR repertoire of matched blood and liver, and resting and activated, human MAIT cells. They id…
Nature Immunology, Published online: 14 August 2023; doi:10.1038/s41590-023-01584-0Streets, Yosef, Robey and colleagues use multiomics analysis to generate a comprehensive timeline of the CD4+ and CD8+ T cell lineage commitment and ide…
Nature Immunology, Published online: 14 August 2023; doi:10.1038/s41590-023-01587-xHere, the authors show that short-term consumption of energy-dense diets deficient in fiber, similar to eating patterns for many people today, results i…
Nature Immunology, Published online: 14 August 2023; doi:10.1038/s41590-023-01596-wThe first detailed investigation of CD8+ tumor-infiltrating T cell differentiation in the hours after cells enter a tumor has yielded an unexpected twis…
Nature Immunology, Published online: 14 August 2023; doi:10.1038/s41590-023-01592-0The functional heterogeneity of macrophages has ontological and microenvironmental bases, and differentially affects pathology. In pancreatitis, tissue-…
Nature Immunology, Published online: 14 August 2023; doi:10.1038/s41590-023-01594-yMalaria is a vector-borne disease caused by Plasmodium parasites. In an exciting new study, Ganley et al. harness the power of mRNA vaccines to summon t…
Nature Immunology, Published online: 10 August 2023; doi:10.1038/s41590-023-01589-9In inflammation, some regulatory T (Treg) cells lose FoxP3 expression and become exTreg cells. Ley and colleagues mapped mouse Treg and exTreg cell tran…