Nature Immunology
γδ stress detectors
Nature Immunology, Published online: 21 September 2023; doi:10.1038/s41590-023-01638-3γδ stress detectors
Nature Immunology
Post-COVID-19 epigenetic signatures
Nature Immunology, Published online: 21 September 2023; doi:10.1038/s41590-023-01639-2Post-COVID-19 epigenetic signatures
Nature Immunology
Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection
Nature Immunology, Published online: 21 September 2023; doi:10.1038/s41590-023-01613-yWherry and colleagues define the kinetics of vaccine-primed recall immune responses during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-…
Nature Immunology
Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
Nature Immunology, Published online: 18 September 2023; doi:10.1038/s41590-023-01646-3Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
Nature Immunology
Multivalent virus-like epitope display amplifies BCR signaling independent of avidity
Nature Immunology, Published online: 18 September 2023; doi:10.1038/s41590-023-01619-6We show that multivalent epitope display on the surface of viral-sized particles functions as a ‘stand-alone’ danger signal by evading inhibitory pat…
Nature Immunology
Nutrition impact on ILC3 maintenance and function centers on a cell-intrinsic CD71–iron axis
Nature Immunology, Published online: 14 September 2023; doi:10.1038/s41590-023-01612-zIron metabolism has been shown to play an important role in the development and function of the immune system, but its role in ILC3s is unclear. Here…
Nature Immunology
Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8<sup>+</sup> T cell exhaustion
Nature Immunology, Published online: 14 September 2023; doi:10.1038/s41590-023-01614-xVerdeil and colleagues show that the transcription factor NFAT5 is selectively required in tumor-induced, but not chronic infection-induced, CD8+ T c…
Nature Immunology
Cancer- and infection-induced T cell exhaustion are distinct
Nature Immunology, Published online: 14 September 2023; doi:10.1038/s41590-023-01624-9The transcription factor NFAT5 regulates T cell exhaustion, a dysfunctional state caused by chronic exposure to antigen and other signals, during can…
Nature Immunology
Disorder-based T cell developmental order
Nature Immunology, Published online: 14 September 2023; doi:10.1038/s41590-023-01623-wMany transcription factors contain intrinsically disordered regions whose functions are not well characterized. An intrinsically disordered region in…
Nature Immunology
Control of nutrient uptake by IRF4 orchestrates innate immune memory
Nature Immunology, Published online: 11 September 2023; doi:10.1038/s41590-023-01620-zSantosa et al. show that IRF4 is upregulated upon NK cell activation and acts as a signal integrator for the differentiation and expansion of mouse c…