Nature Immunology, Published online: 12 October 2023; doi:10.1038/s41590-023-01645-4Here, the authors show that deletion of Pglyrp1 promotes antitumor immunity owing to its inhibitory function in CD8+ T cells and that targeting it can …
Nature Immunology, Published online: 12 October 2023; doi:10.1038/s41590-023-01607-wSantosa and Sun draw parallels from T cell biology to explore the key features of immune memory in innate lymphocytes.
Nature Immunology, Published online: 12 October 2023; doi:10.1038/s41590-023-01644-5Eisenlohr and colleagues identify a novel influenza A virus peptide that elicits a robust CD8+ T cell response and is restricted by the nonclassical Qa…
Nature Immunology, Published online: 12 October 2023; doi:10.1038/s41590-023-01643-6Genetic and environmental diversity are major drivers of macrophage transcriptional responses, but the mechanisms that underlie the relative contributi…
Nature Immunology, Published online: 12 October 2023; doi:10.1038/s41590-023-01649-0Immune checkpoint inhibitors provide beneficial anti-tumor immunity but risk immune-related adverse events occurring in normal tissues. Notably, select…
Nature Immunology, Published online: 11 October 2023; doi:10.1038/s41590-023-01674-zPublisher Correction: Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflamm…
Nature Immunology, Published online: 09 October 2023; doi:10.1038/s41590-023-01636-5The malate shuttle is understood to control the NAD+/NADH balance. Here the authors show that GOT1, a central enzyme in the malate shuttle, rather prom…
Nature Immunology, Published online: 09 October 2023; doi:10.1038/s41590-023-01634-7Yuan and colleagues show that ERMAP expression on cancer cells delivers an ‘eat me’ signal to Kupffer cells by binding to Gal-9–dectin-2 on Kupffer cel…
Nature Immunology, Published online: 09 October 2023; doi:10.1038/s41590-023-01647-2Kupffer cells, hepatic resident macrophages, are the first line of defense against liver metastases by engulfing disseminated malignant cells. We found…
Nature Immunology, Published online: 09 October 2023; doi:10.1038/s41590-023-01650-7For decades, beta-blockers have been used widely to treat cardiovascular diseases. Surprisingly, new data show how these inhibitors can also improve im…