Nature Immunology, Published online: 20 November 2023; doi:10.1038/s41590-023-01666-zMandal and colleagues report how the chromatin modulator BRWD1 mediates extensive changes in 3D chromatin topology during B cell development by conver…
Nature Immunology, Published online: 16 November 2023; doi:10.1038/s41590-023-01681-0Interleukin-27 (IL-27) is a pleiotropic cytokine known for its diverse immune regulatory properties. Although innate immune cells are considered the m…
Nature Immunology, Published online: 13 November 2023; doi:10.1038/s41590-023-01668-xIwawura et al. identify a noncanonical role for NOD1, independent from its CARD-mediated proteoglycan sensing. Interactions between NOD1 and STAT5 are…
Nature Immunology, Published online: 13 November 2023; doi:10.1038/s41590-023-01673-0Cancer cells often overexpress CD47, which triggers the macrophage receptor SIRPα to elude anti-tumor immunity. We found that CD47 also suppresses pha…
Nature Immunology, Published online: 09 November 2023; doi:10.1038/s41590-023-01663-2Love and colleagues find an inhibitory function for CD3ζ ITAMs in response to low-affinity ligands, meaning that CD3ζ can perform a dual function in T…
Nature Immunology, Published online: 09 November 2023; doi:10.1038/s41590-023-01655-2Luster and colleagues report that lung-resident ST2+ regulatory T cells secrete the IL-1 antagonist IL-1Ra to suppress neutrophils and early innate im…
Nature Immunology, Published online: 09 November 2023; doi:10.1038/s41590-023-01671-2Veillette and colleagues show that CD47 on tumor cells interacts in cis with the pro-phagocytic ligand SLAMF7, masking the ability of SLAMF7 to engage…
Nature Immunology, Published online: 07 November 2023; doi:10.1038/s41590-023-01699-4Publisher Correction: Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR–RUNX1
Nature Immunology, Published online: 06 November 2023; doi:10.1038/s41590-023-01669-wMathis and colleagues identify a subset of muscle mesenchymal stromal cells that coordinates tissue immune responses and drives regenerative mechanism…
Nature Immunology, Published online: 06 November 2023; doi:10.1038/s41590-023-01658-zMinguet and colleagues systematically examine how individual CD3 chains of the TCR–CD3 complex can improve chimeric antigen receptor (CAR) T cell perf…