Nature Immunology
Anaphylactic degranulation by mast cells requires the mobilization of inflammasome components
Nature Immunology, Published online: 14 March 2024; doi:10.1038/s41590-024-01788-yAbraham and colleagues found that antigen-triggered degranulation in IgE-sensitized mast cells was mediated by the inflammasome components NLRP3 and ASC.