Nature Immunology, Published online: 25 June 2024; doi:10.1038/s41590-024-01872-3In this Review, the authors summarize the literature around immune cancer cell STING signaling and how it is finely balanced between pro-tumorigenic and a…
Nature Immunology, Published online: 25 June 2024; doi:10.1038/s41590-024-01880-3Humanized mice have been a valuable tool for modeling human immunology but are limited in their ability to model human antibody responses. Here the author…
Nature Immunology, Published online: 25 June 2024; doi:10.1038/s41590-024-01889-8Improved understanding of CD8+ T cell function during HIV infection is vital to designing an HIV cure. We have identified a subset of lymph node CD8+ T ce…
Nature Immunology, Published online: 25 June 2024; doi:10.1038/s41590-024-01869-yIL-1R1 signaling in neural stem cells reduces hippocampal neurogenesis in adult mice, potentially affecting learning and memory. Using a new mouse model, …
Nature Immunology, Published online: 24 June 2024; doi:10.1038/s41590-024-01867-0Viiri and colleagues show that an orally administered transglutaminase 2 inhibitor prevented gluten-induced intestinal damage and inflammation at the tran…
Nature Immunology, Published online: 21 June 2024; doi:10.1038/s41590-024-01881-2Dendritic cells migrate to and from lymph nodes in response to chemokine gradients.Data now show that steady-state migration of these cells can be trigger…
Nature Immunology, Published online: 20 June 2024; doi:10.1038/s41590-024-01868-zSARS-CoV-2 has been shown to induce IL-1β-mediated neuroinflammation in humans and rodent models. Klein and colleagues show that low-dose COVID-19 vaccina…
Nature Immunology, Published online: 19 June 2024; doi:10.1038/s41590-024-01860-7Li et al. identify a human TCF1-expressing stem-like T cell population that is associated with immune-mediated pathogenesis in ulcerative colitis.
Nature Immunology, Published online: 19 June 2024; doi:10.1038/s41590-024-01879-wVariation in inter-individual immune phenotypes can be influenced by both genetics and environmental factors. Using a range of different inbred strains of…
Nature Immunology, Published online: 17 June 2024; doi:10.1038/s41590-024-01875-0Paiardini and colleagues describe a subset of lymph node HIV- and SIV-specific TOXhiTCF1+CD39+CD8+ T cells that coexhibit stem- and effector-like phenotyp…