Nature Immunology, Published online: 03 December 2025; doi:10.1038/s41590-025-02345-xCao et al. provide a comprehensive immune landscape of sepsis, delineating anatomical-specific and age-dependent programs.
Nature Immunology, Published online: 01 December 2025; doi:10.1038/s41590-025-02380-8Author Correction: Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity
Nature Immunology, Published online: 28 November 2025; doi:10.1038/s41590-025-02343-zThe authors identify a Cys→Ser transformation (C19S) in insulin leading to neoepitope presentation and CD4⁺ T cell autoreactivity in type 1 diabetes. …
Nature Immunology, Published online: 28 November 2025; doi:10.1038/s41590-025-02375-5Author Correction: Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia
Nature Immunology, Published online: 24 November 2025; doi:10.1038/s41590-025-02361-xStabilizing iTreg cells
Nature Immunology, Published online: 24 November 2025; doi:10.1038/s41590-025-02360-yDistal directives
Nature Immunology, Published online: 24 November 2025; doi:10.1038/s41590-025-02362-wBreastfeeding induces protective T cells
Nature Immunology, Published online: 24 November 2025; doi:10.1038/s41590-025-02325-1Klose and colleagues show that the neuropeptide vasoactive intestinal peptide (VIP) acts on LGR5+ epithelial stem cells in the gut to restrain their p…
Nature Immunology, Published online: 11 April 2025; doi:10.1038/s41590-025-02126-6Sexual dimorphism is a feature of many cancers, but how this functions is often unclear. Here the authors show that in bladder cancer it is regulated by …
Nature Immunology, Published online: 10 April 2025; doi:10.1038/s41590-025-02141-7A fine balance is needed for Treg cells to enable immune responses to pathogens without triggering autoimmunity. Data now show that thymus-derived self-p…