Nature Chemical Biology, Published online: 04 July 2022; doi:10.1038/s41589-022-01048-wAldehyde dehydrogenase 1B1-specific small-molecule inhibitors are identified that block the growth of colon cancer spheroids and organoids and are s…
Nature Chemical Biology, Published online: 04 July 2022; doi:10.1038/s41589-022-01061-zThe marine compound microcolin B stimulates the Hippo pathway and selectively kills YAP-dependent cancer cells by inhibiting phosphatidylinositol tr…
Nature Chemical Biology, Published online: 04 July 2022; doi:10.1038/s41589-022-01066-8The Hippo pathway is a key regulator of tissue homeostasis, organ size and cancer. Identification of microcolin B and its analog molecules as Hippo …
Nature Chemical Biology, Published online: 27 June 2022; doi:10.1038/s41589-022-01046-yThis Perspective discussed selective partitioning behaviors of biomolecules and small molecules and proposed that understanding the chemical propert…
Nature Chemical Biology, Published online: 27 June 2022; doi:10.1038/s41589-022-01080-wBacterial data loggers
Nature Chemical Biology, Published online: 27 June 2022; doi:10.1038/s41589-022-01078-4IFN interference
Nature Chemical Biology, Published online: 27 June 2022; doi:10.1038/s41589-022-01081-9A home for orphans
Nature Chemical Biology, Published online: 27 June 2022; doi:10.1038/s41589-022-01079-3Hold the LINE
Nature Chemical Biology, Published online: 14 March 2022; doi:10.1038/s41589-022-00981-0Identification of venom insulins with A-chain elongations inspired hybrid analogs with similar activity to human insulin. Cryo-EM structure analysi…
Nature Chemical Biology, Published online: 14 March 2022; doi:10.1038/s41589-022-00983-yCharacterization of the polysaccharide utilization loci from two Bacteroides species from the human gut microbiota define biochemical and structura…