Nature Chemical Biology, Published online: 08 August 2022; doi:10.1038/s41589-022-01095-3Merging the generalized extracellular molecule sensor (GEMS) system with screening designed ankyrin repeat proteins (DARPins) identifies an advanc…
Nature Chemical Biology, Published online: 05 August 2022; doi:10.1038/s41589-022-01132-1Author Correction: Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota
Nature Chemical Biology, Published online: 04 August 2022; doi:10.1038/s41589-022-01089-1A FRET-based assay using the conserved tryptophans of bacterial quorum-sensing LuxR-type proteins and synthetic fluorophore-acyl-homoserine lacton…
Nature Chemical Biology, Published online: 01 August 2022; doi:10.1038/s41589-022-01077-5A hypercompact adenine base editor termed TaRGET-ABE was developed by fusing a catalytically inactive transposon-associated transposase B guided b…
Nature Chemical Biology, Published online: 01 August 2022; doi:10.1038/s41589-022-01101-8Transposon-associated transposase B (TnpB) is the putative ancestor of Cas nucleases. A TnpB-based adenine base editor has now been developed that…
Nature Chemical Biology, Published online: 27 July 2022; doi:10.1038/s41589-022-01088-2Emerging evidence shows that ubiquitination can occur on nonlysine residues and nonproteinaceous substrates. This perspective summarizes the recent …
Nature Chemical Biology, Published online: 25 July 2022; doi:10.1038/s41589-022-01106-3Altering the cap
Nature Chemical Biology, Published online: 25 July 2022; doi:10.1038/s41589-022-01105-4Cutting back
Nature Chemical Biology, Published online: 25 July 2022; doi:10.1038/s41589-022-01104-5Choosing the junk
Nature Chemical Biology, Published online: 21 July 2022; doi:10.1038/s41589-022-01065-9The discovery of a strained β-lactone electrophile that covalently targets a KRAS G12 somatic mutation and acylates the mutant serine to suppress on…