Nature Chemical Biology, Published online: 01 September 2022; doi:10.1038/s41589-022-01114-3Dynamic redundancy by horizontal gene transfer stabilizes gene abundances amidst compositional fluctuations in microbial communities, which sug…
Nature Chemical Biology, Published online: 25 August 2022; doi:10.1038/s41589-022-01111-6Using methyl group and fluorine NMR spectroscopic methods, Overbeck et al revealed that the dynamics of the eukaryotic 5′→3′ exoribonuclease Xrn2 …
Nature Chemical Biology, Published online: 24 August 2022; doi:10.1038/s41589-022-01146-9Author Correction: Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux
Nature Chemical Biology, Published online: 22 August 2022; doi:10.1038/s41589-022-01096-2Microtubule-associated proteins tau and MAP2 cooperatively form protein envelopes that compact the underlying tubulin lattice, revealing a novel r…
Nature Chemical Biology, Published online: 22 August 2022; doi:10.1038/s41589-022-01097-1The microtubule-associated protein tau is strongly linked to Alzheimer’s disease, but the physiological functions of tau on microtubules remain un…
Nature Chemical Biology, Published online: 22 August 2022; doi:10.1038/s41589-022-01102-7Evybactin is an antimicrobial natural product that targets DNA gyrase, where it binds to a site overlapping with synthetic thiophene poisons and e…
Nature Chemical Biology, Published online: 22 August 2022; doi:10.1038/s41589-022-01103-6Photorhabdus noenieputensis (a gut microbiota symbiont of nematodes) produces a macrocyclic antibiotic, evybactin, that selectively kills Mycobact…
Nature Chemical Biology, Published online: 22 August 2022; doi:10.1038/s41589-022-01123-2A chilling effect
Nature Chemical Biology, Published online: 22 August 2022; doi:10.1038/s41589-022-01125-0Cyclic signature
Nature Chemical Biology, Published online: 22 August 2022; doi:10.1038/s41589-022-01124-1Protecting with PROTAC