Nature Chemical Biology

Nature Chemical Biology, Published online: 18 September 2024; doi:10.1038/s41589-024-01746-7Sweet RNA

Nature Chemical Biology, Published online: 18 September 2024; doi:10.1038/s41589-024-01745-8Anti-aggregate activity

Nature Chemical Biology, Published online: 18 September 2024; doi:10.1038/s41589-024-01747-6Breaking down taurine

Nature Chemical Biology, Published online: 16 September 2024; doi:10.1038/s41589-024-01736-9Naturally occurring peptide–nucleobase hybrids are rare. Here Pei et al. report the discovery and biosynthetic studies of the first peptide–nuc…

Nature Chemical Biology, Published online: 16 September 2024; doi:10.1038/s41589-024-01711-4A modular multicellular system has been created by mixing and matching discrete engineered bacterial cells in an artificial neural network-type…

Nature Chemical Biology, Published online: 13 September 2024; doi:10.1038/s41589-024-01735-wThe incorporation of nitrogen in steroidal glycoalkaloids is hypothesized to occur through a transamination reaction. Here, the authors show th…

Nature Chemical Biology, Published online: 12 September 2024; doi:10.1038/s41589-024-01737-8Superoxide oxidizes the iron–sulfur cluster in the DNA demethylase ROS1 and extensively participates in the establishment of active DNA demethy…

Nature Chemical Biology, Published online: 12 September 2024; doi:10.1038/s41589-024-01733-yCaliendo and Vitu et al. developed a platform for endogenous gene expression monitoring and conditional actuator activation, by integrating non…

Nature Chemical Biology, Published online: 11 September 2024; doi:10.1038/s41589-024-01727-wHow a lasso cyclase ties a lasso peptide into its characteristic knot has remained poorly understood. Here the authors identify key molecular i…

Nature Chemical Biology, Published online: 11 September 2024; doi:10.1038/s41589-024-01712-3By enriching productive mutational paths, a Kemp eliminase that speeds up proton abstraction >108-fold was developed in only five evolution rou…