Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1

Publication date: Available online 30 June 2022Source: Journal of Biological ChemistryAuthor(s): Sumit J. Bandekar, Chun-Liang Chen, Sandeep K. Ravala, Jennifer N. Cash, Larisa V. Avramova, Mariya V. Zhalnina, J. Silvio Gutkind, Sheng Li, John J.G. Tesmer

A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of <em>Trichomonas vaginalis</em>

Publication date: Available online 30 June 2022Source: Journal of Biological ChemistryAuthor(s): Evana N. Abdulaziz, Tristan A. Bell, Bazlur Rashid, Mina L. Heacock, Tarik Begic, Owen S. Skinner, Mohammad A. Yaseen, Luke H. Chao, Vamsi K. Mootha, Anton…

Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways

Publication date: July 2022Source: Journal of Biological Chemistry, Volume 298, Issue 7Author(s): Mizuki Aoki, Jeffrey Vinokur, Kento Motoyama, Rino Ishikawa, Michael Collazo, Duilio Cascio, Michael R. Sawaya, Tomokazu Ito, James U. Bowie, Hisashi Hemmi